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However, the inhibition of -GCS activity by GSH is of physiological significance [7] and is the rate-limiting step in GSH biosynthesis

285 , 723730 (2010) Runge, S., Thgersen, H., Madsen, K., Lau, J

First, one notable limitation of our study is the small sample size, which may reduce the generalizability of the findings to a broader population and prevented the possibility to conduct sub-group analysis