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[26] have speculated long-term GIP receptor agonism results in significant GIP receptor downregulation and effectively leads to GIP receptor antagonism with the effect of reduced food intake
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This article compares mechanism, trial status, weight-loss evidence, diabetes relevance, tolerability questions, and approval outlook
Competing Interest The author(s) declare that there are no potential conflicts of interest with respect to the research, authorship, and/or publication of this article
The Metabolic Phenotype in Obesity: Fat Mass, Body Fat Distribution, and Adipose Tissue Function
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