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The medication is contraindicated in patients with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2

Most enzyme changes seen during GLP-1 therapy are actually secondary to rapid weight loss itselfas fat leaves liver cells, transient enzyme fluctuations can appear on blood work without indicating true hepatic damage

These numbers surpassed every other weight loss medication on the market at the time of publication

Constipation or diarrhea Bowel habits are a bit different for everyone, but if you are having infrequent number two episodes and pain, cramping, or bloating, you might be experiencing constipation

The goal in every case is the same: activate enough GLP-1 receptor signaling to reduce appetite without triggering the dose-dependent side effects that make higher doses difficult to tolerate