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These actions may help maintain a healthy intestinal environment, promote healthy inflammatory markers and support metabolic functions
Both do have side effects, mostly digestive
Data suggest GLP-1s help clear toxic proteins, reduce inflammation, improve brain energy use, and protect cell connections
In vivo, retatrutide produced significant reductions in body weight, adiposity, and blood glucose levels in diet-induced obese mouse models, outperforming dual GIP/GLP-1 agonists through the additional thermogenic and energy-expenditure effects mediated by glucagon receptor activation
