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Sinomenine improve diabetic nephropathy by inhibiting fibrosis and regulating the JAK2/STAT3/SOCS1 pathway in streptozotocin-induced diabetic rats

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Discussion Our findings demonstrate that GLP-1 receptor agonist-based therapeutics significantly disrupt the interoceptive stimulus effects of alcohol, highlighting a potential therapeutic mechanism through which these medications may reduce alcohol consumption and motivation

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Mechanistically, choline and methionine relate to hepatic fat transport and one-carbon metabolism

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