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Published literature can help define research context, but it should not be converted into product-use claims

Funding The research was supported in part by Grants-in-Aid for Challenging Exploratory Research and Scientific Research (B) from the Japan Society for the Promotion of Science (JSPS KAKENHI Grant Numbers JP26660218, JP21H02347, and JP24K01911, respectively) and by grant funds from the Uehara Memorial Foundation and Ito Foundation (all to R

10.1126/science.aaw5473 77 FaubertB.VincentE

Therapeutic targeting of transport-mediated resistance Given the central role of efflux transporters in mediating MDR, extensive efforts have been dedicated to the development of pharmacological strategies aimed at overcoming transporter-driven drug efflux

This acid attracts and binds moisture from the environment into the skin , pumping up its hydration levels