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Results become more predictable
Individuals who are heterozygous for GBA pathogenic variants though have an increased risk of parkinsonism and dementia (Tayebi et al
Moreover, they activate the MAPK11RBBP6SIRT6 axis, which upregulates GLS1 and PYCR1, reprogramming tumor metabolism and creating a prosurvival microenvironment through aspartate and proline secretion
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![List of current GLP-1 and its analogs [36-39]](https://www.researchgate.net/publication/371322849/figure/tbl1/AS:11431281165596278@1686056417230/List-of-current-GLP-1-and-its-analogs-36-39.png)
