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It is encoded by mitochondrial DNA, making it one of only a handful of known mitochondria-derived peptides
Chemical Makeup Molecular Formula: C 78 H 123 N 23 O 23 S 2 Molecular Weight: 1815.12 g/mol Other Known Titles: Tyr-hGH Fragment 177-191 Research and Clinical Studies AOD 9604 Peptide and Lipolytic Activity Early studies were carried out on obese mice where the AOD 9604 peptide was periodically introduced for 14 days
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PMID 16249424
In dermal wound trials, TB4 has been explored for accelerating re-epithelialization, and is under investigation in ocular injury models (e.g., corneal wound healing)
