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We prioritized genes belonging to several biological classes related to kidney function based on: missense variants (either the lead or a proxy variant, 34 genes), DEPICT gene prioritization results (156 genes), significantly colocalized eQTLs in either kidney (4 genes) or non-kidney (187 genes) tissue, or nearby Mendelian kidney-disease genes (Supplementary Tables 12, Supplementary Data 24)

[9] The Current State of Peptide Drug Discovery: Back to the Future

When we first built our weight loss solution, we prioritized access to non-GLP-1 treatments, including some that had been used for decades to successfully help people lose weight

A malignant peripheral nerve sheath tumor is a cancerous peripheral nerve sheath tumor, which is frequently resistant to conventional treatments