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[1] [3] Tirzepatide functions as a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist
NEJM 2025 (REDEFINE-1) Davies MJ, et al
Retatrutide Retatrutide is a next-generation triple receptor agonist that acts on GLP-1, GIP, and glucagon pathways and is currently being studied for weight management, appetite regulation, insulin sensitivity, metabolic health, and body composition support
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