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Users make personal decisions about a compound that research supports but regulators have not approved

doi: 10.1056/NEJM197808312990901 3 UngerRHCherringtonAD

Hanna Lee, an endocrinologist at Lenox Hill Hospital in New York City, says those flare-ups are often temporary

These combined factorshigh dropout rates, early plateaus, and widespread patient frustrationhighlight the limitations of behavioral therapy alone and suggest that earlier pharmacological intervention might provide more effective and humane treatment for individuals struggling with obesity

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