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Whether youre dealing with a deficiency or looking to maintain your well-being, B12 shots can make a significant impact

That makes it the most cost-effective vial size for most researchers

The FDA label says to take it "on an empty stomach in the morning with up to 4 ounces of water," then "wait at least 30 minutes before eating food, drinking beverages or taking other oral medications." Miss that window and the dose may not absorb well

But the inability to replicate meaningful results in a larger, longer trial raises legitimate questions about the magnitude and reliability of the fat loss effect