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I recommend having hormone levels checked, usually through a specialized saliva testing system that we utilize in my practice

Standard volumes are 1mL, 2mL, 3mL, and 5mL

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However, its important to note that these studies were done in vitro (in a test tube/culture), not in humans

Most patients start to notice a brighter, more even tone after a few sessions, with fuller results over a course spaced roughly one to two weeks apart