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In a study by Malinda et al
[5] Disruption of these pathways leads to accumulation of homocysteine and methylmalonic acid, metabolic signatures linked to megaloblastic anemia and demyelinating neuropathy
There is a large potential for variation in results according to the assay used, and support for the authenticity of a given assay is best generated by showing a correlation with an in vivo outcome
& Fishel, S
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