GLP-1 administration induces visceral illness in both rodents (Seeley et al., GLP-1R regulation of food reward In addition to being expressed in hypothalamic areas that regulate homeostatic feeding, the GLP-1R is expressed in areas that mediate food reward in both rodents (Merchenthaler et al., GLP-1R action on brown adipose tissue (BAT) thermogenesis In addition to causing changes in feeding, central GLP-1R activation may regulate body weight by increasing brown adipose tissue (BAT) thermogenesis (reviewed in Lockie et al., GLP-1R action on neuroprotection GLP-1R analogs have neuroprotective and anti-inflammatory properties, which may be contributing the beneficial effects on energy metabolism (reviewed in Holscher, Effectiveness of GLP-1R agonists on weight loss in humans Despite not have a complete understanding of the underlying molecular mechanisms, GLP-1R activation clearly has beneficial effects on both energy and glucose metabolism across a number of species

They change your digestion, reduce your appetite, and shift how your body uses fuel
The best results come from consistent treatmentsusually once or twice a week for 8-12 weeks, then maintenance treatments monthly
However, as with many vitamins, getting too much can lead to health complications
Journal of Dental Anesthesia and Pain Medicine, 22 (2), 97