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Phase 3 data on retatrutide (triple GLP-1/GIP/glucagon agonist) showing nearly 29% weight loss, the pending approval of CagriSema (GLP-1/amylin combination), and the arrival of oral non-peptide GLP-1 agonists like orforglipron all suggest we are at the start of a metabolic therapeutics renaissance
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Baseline signal was measured for 5 min at 37C using a Flexstation 3 plate reader with the following settings: ex = 335 nm, em = 490 and 590 nm, delay 50 s
This is where I want to be very clear, because the enthusiasm around this drug sometimes drowns out the contraindications
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