In combination with glimepiride, with or without metformin, the overall incidence of clinical adverse reactions with Januvia was higher than with placebo, in part related to a higher incidence of hypoglycemia (see Table 1)
It does contain some saturated fat, too, so portion control matters
The micro-channels created by the tiny needles improve penetration, so you increase bioavailability without the need for injection, which is where things get considerably murkier
However, it has also been shown to be highly effective for weight loss, making it a valuable tool for patients struggling with both diabetes and obesity
If oral rehydration fails or mental status changes occur, patients should seek emergency services without delay