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Instead, it is more appropriate to envision metabolic plasticity regarding uptake of alternative metabolic substrates and promotion of metabolic rewiring as a built-in feature that has evolved to allow cancer cells to constantly adapt to changing intracellular- and extracellular metabolic conditions 2

Telomeres, the protective caps at the end of chromosomes, naturally shorten with age, leading to cellular aging and reduced function

Glutathione (GSH) is an enzymatically derived intracellular tripeptide: -glutamyl-cysteinyl-glycine: -glu-cys-gly or -ECG

Potential pathways clinicians consider in similar contexts include: Blood pressure changes, including nocturnal hypotension NAION has been associated in some literature with low nighttime blood pressure