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Phase II clinical trials in patients with sarcoidosis-related small fiber neuropathy demonstrated significant increases in corneal nerve fiber density (a reliable surrogate marker for systemic small fiber health) alongside meaningful reductions in neuropathic pain scores

10,56 Regenerative Therapies Regenerative approaches to IC/BPS have gained attention in recent years

While BPC-157 circulates systemically regardless of administration route, local injection creates a concentration gradient favoring the target area

SLU-PP-332 is a chemically tractable agonist developed to engage ERR//, with highest potency at ERR and measurable activity on ERR and ERR