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Secondary endpoints included the change from baseline to EOS in body weight (kg), proportion of participants achieving HbA1c level 5% (76.4%
Current clinical guidance recommends: Discontinuing Wegovy at least 2 months before attempting conception to allow full clearance Continuing reliable contraception until actively trying to conceive, given that weight loss may restore ovulation unexpectedly Stopping the medication immediately and consulting a provider upon confirmed pregnancy For women with PCOS planning pregnancy, coordinating a transition plan with both gynecology and endocrinology before stopping Wegovy Wegovy and breastfeeding No human safety data exists for semaglutide use during breastfeeding
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