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Healthy adults were supplemented with ascorbate to better understand the vitamins effects on GSH homeostasis

Flack JM, Agarwal R, Anker SD, et al

Additionally, the FDA recommends that these medications not be taken during pregnancy and be discontinued at least two months prior to pregnancy, because studies in rats, rabbits, and monkeys demonstrated that animals treated with these medications had higher rates of miscarriage, were born smaller, and were more likely to have birth defects

Eat Smaller, More Frequent Meals: To combat nausea, avoid eating large volumes at once