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When combining GLP-1 receptor agonists with insulin or sulfonylureas, the chance of experiencing hypoglycemia (low blood sugar) goes up

Recombinant lines expressing a single melanocortin receptor subtype are the cleanest system available, and for a non-selective agonist they are close to essential, because they are the only way to attribute a response to one receptor without pharmacological subtraction

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Mild to moderate hypertension (alone or in combination with other antihypertensive) & in the treatment of chronic stable and vasospastic angina

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