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Other licensed pharmacological options : For patients unsuitable for or unable to tolerate Wegovy, alternatives include: Orlistat (lipase inhibitor that reduces fat absorption) Liraglutide 3mg (another GLP-1 receptor agonist, recommended by NICE TA664 for specific patient groups, though local NHS availability may vary) Consideration of bariatric surgery referral for eligible patients with severe obesity Medically supervised diets : If rapid weight loss is clinically indicated (e.g., pre-bariatric surgery), options include: Very low-calorie diets (800 kcal/day) under specialist supervision for up to 12 weeks Low-calorie diets (8001200 kcal/day) with appropriate nutritional support These differ fundamentally from HCG protocols as they provide adequate protein, vitamins, and minerals and are used within NHS-approved frameworks
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The before-bed timing amplifies the natural nocturnal GH surge, the largest pulse of the day
Clinical Versatility: Ideal for dissolving or diluting compatible vaccines, peptides, and other injectable medications
Some patients report headache, changes in sleep patterns, mild nausea, or mood fluctuation during the first week
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