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Oxidative stress may contribute to processes involved in cardiovascular disease, including endothelial dysfunction, LDL oxidation, inflammation, mitochondrial injury, and plaque formation

J Mol Med (Berl, Ger)

doi:10.1093/asj/sjac007

With a mechanism related to Ca++ influx, tamoxifen appears to operate through Ca++-sensitive PKCs, including prkca, prkcbi, prkcbii and prkcg (Radin and Patel, 2016)