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Oxyntomodulin Oxyntomodulin, a longer isoform of glucagon, is a dual agonist of the GLP-1 and glucagon receptors, though with a 10- to 100-fold lower affinity than the native ligands (80, 81)

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The pharmacokinetics also explain why blood levels rise gradually and reach steady state after ~45 weekly doses, at which point effects feel more consistent

Aim for the higher end of recommendations when losing weight, targeting approximately 1.2 to 1.6 grams of protein per kilogram of body weight daily to preserve lean mass