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No human trial has shown Akkermansia to be a weight-loss treatment, and the same trial did not meet its main insulin-sensitivity goal across the group as a whole, with benefits showing up mainly in people who started with low Akkermansia levels or who had prediabetes

Note: medications can only be shipped to California addresses due to regulatory requirements

Asian-Australas J Anim Sci

Gastric Emptying Delay: By slowing gastric emptying, GLP-1 agonists help prolong feelings of fullness after meals

The likely mechanism is that GLP-1 receptor agonists slow gastric emptying and reduce peristalsis the rhythmic muscular contractions that move stool through the colon