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Sekizawa T, Openshaw H, Ohbo K, Sugamura K, Itoyama Y, Niland JC
The peptides development was ultimately discontinued in 2007 after a 24-week Phase III trial failed to demonstrate statistically significant weight loss compared to placebo, though research into its regenerative properties has continued
independent Western replication is minimal
FOXO proteins undergo various post-translational modifications (phosphorylation, acetylation, ubiquitination, methylation, glycosylation) that influence their biological function in the central nervous system
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