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UPR activation varies across different brain regions and disease contexts, reflecting the selective vulnerability of neuronal populations

However, one must balance this with not eating too heavily or too late at night ( Dietary polyphenols and antioxidant-rich foods are primarily addressed as components of dietary patterns that support physiological resilience and redox balance during aging

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Researchers exploring vitamin C and peptides or other micronutrient strategies should tailor supplementation to individual needs based on testing

Lancet Diabetes Endocrinol (2022) 10:393406