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Unlike many pharmaceutical compounds, GHK-Cu does not appear to produce tolerance with continued use
Pharmacol Rev 76:12911325
However, some individuals may experience: Injection site reactions such as mild redness, itching, or swelling Water retention or mild fluid buildup, particularly in the early weeks Joint discomfort or stiffness, which often resolves as the body adjusts Tingling or numbness in the hands or feet (less common) Elevated blood glucose levels in individuals predisposed to insulin resistance It is worth noting that tesamorelin should not be used by individuals with active cancer, those who are pregnant, or patients with hypersensitivity to its components
This combined approach makes BPC-157 of additional interest within broader research protocols
Anti-inflammatory & cytoprotective actions (GI and beyond)
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