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The limitation belongs in the same breath as the finding

[5] In the same 28-day study, DIO mice showed reduced body weight and fat mass gains alongside improved glucose tolerance and attenuated hepatic steatosis

B12 deficiency is more common than widely recognized, particularly in individuals who follow plant-based diets, take proton pump inhibitors or metformin, are over 50, or have gastrointestinal conditions affecting absorption

Given its involvement in almost every cell, a deficiency in Vitamin B12 can quickly lead to significant health problems

This dual action may be essential in contexts where dermal integrity is challenged, as a robust extracellular matrix provides not only mechanical support but also biochemical cues necessary for optimal cell function