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The peptide upregulates genes involved in collagen synthesis, including COL1A1 (Type I collagen), COL3A1 (Type III collagen), and COL4A1 (Type IV collagen)

Jan Garfinkle, MBA Founder and Managing Partner, Arboretum Ventures Jan Garfinkle, MBA Founder and Managing Partner, Arboretum Ventures Ms

Sprong RC, Winkelhuyzen-Janssen AM, Aarsman CJ, van Oirschot JF, van der Bruggen T, van Asbeck BS

At higher concentrations, MMP2 and MMP9 decrease in ischemic wounds, preventing excessive collagen degradation that would impair healing

The reaction was quenched the same way as for the thioredoxin experiment and the samples were analyzed on acrylamide gels and quantified with ImageJ software