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Mycophenolate mofetil (MMF) treatment has been shown to prevent or attenuate ischemic injury and autoimmune myocarditis in animal models, with reduced secretion of inflammatory markers such as TLR4, NFB, BAX expression, and TNF ( Mitochondrial dysfunction Mitochondria constitute a third of cardiomyocyte volume, and the heart, as a metabolically active organ, relies heavily on mitochondrial ATP production (79)

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