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Ninety healthy individuals were enrolled in this study
CJC-1295 is hypothesized to bind to GHRH receptors on pituitary somatotroph cells potentially inducing a conformational change that initiates intracellular signaling events including the activation of G-proteins, production of secondary messengers such as cAMP and IP3, and ultimately the fusion of growth hormone-containing vesicles with the plasma membrane and their release into the extracellular environment in laboratory models
Tosukhowong et al
Front Biosci (Schol Ed) (2010) 2:15367
[44]Jozefczak M, Remans T, et al
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