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52 The study by Richie et al gives us important insights into rise in concentrations of glutathione in erythrocytes, plasma, lymphocytes and buccal cells over time
In addition, recent studies indicate that some GLP1R agonists, such as liraglutide, semaglutide, and dulaglutide, exert cardiovascular and renal benefits, and are endorsed for use in patients with these complications
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Ishibashi, Y., Matsui, T., Ojima, A., Nishino, Y., Nakashima, S., Maeda, S., et al.: Glucagon-like peptide-1 inhibits angiotensin II-induced mesangial cell damage via protein kinase A
Liver histological endpointsspecifically, resolution of MASH without worsening of fibrosis, and improvement in liver fibrosis by one or more stage without worsening of MASHare considered appropriate intermediate/surrogate endpoints in regulatory and reimbursement settings, based on current regulatory guidelines
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