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A Claims-Based Study of 30,458 Patients A retrospective cohort study using insurance claims and electronic health records compared 14,101 bariatric surgery patients (mean follow-up 34 months) against 16,357 GLP-1 patients (mean follow-up 32 months), all with class II or III obesity

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These results point to the fact that hypothalamic malonyl-CoA levels likely play a major role in the control of feeding behaviors