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4.4.5 Modulation of the FSP1CoQNADH pathway to inhibit ferroptosis in PD FSP1, originally identified as apoptosis-inducing factor mitochondria-derived 2 (AIFM2), is an NAD(P)H-dependent ubiquinone reductase that functions independently of the canonical GSHGPX4 axis (279)

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This ubiquitous pathological process of oxidative stress is particularly significant in the progression of neurodegenerative disorders including Alzheimer's disease (AD), Parkinson's disease (PD), and Huntington's disease (HD)

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