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Andrew Wilson argues that for a significant minority, "amphetamines symbolised the smart, on-the-ball, cool image" and that they sought "stimulation not intoxication [...] greater awareness, not escape" and "confidence and articulacy" rather than the "drunken rowdiness of previous generations." [113] Dextroamphetamine's dopaminergic (rewarding) properties affect the mesocorticolimbic circuit

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These treatments are currently undergoing clinical trials for expanded usage in pediatric populations and to target broader cardiometabolic and liver conditions, thus rapidly expanding the treatable patient pool

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