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They typically contain 2 to 50 amino acids, making them smaller and easier to absorb by the body compared to full proteins
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Its proline-rich sequence contributes to unusual conformational stability and protease resistance versus typical short peptides
Gastrointestinal effects: the main titration bottleneck Nausea, diarrhea, constipation, and vomiting run around 40 to 44% overall, dose-dependent in how many people report them but mild-dominant in severity: severe events stay at or below about 1.7% in any category even at the top dose. In the obesity program the by-dose rates run nausea 25/29/28%, diarrhea 19/21/23%, and vomiting 8/11/13% at 5/10/15 mg. They concentrate during escalation and ease with time on a held dose
In either event, the fact remains: Vitamin B12 is a serious deficiency that can lead to multiple negative side effects
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