As with any injection, mild side effects can occur, and rare allergic reactions are possible
The Tissue Profile of Metabolically Active Coenzyme Forms of Vitamin B12 Differs in Vitamin B12-Depleted Rats Treated With Hydroxo-B12 or Cyano-B12
Heat above 25C can also potentially be a problem, although less so
Good absorption Provided a patient has good circulation, complete absorption often occurs using this method
(Outlines contraindications for niacin therapy, including active peptic ulcer disease, active liver disease with elevated enzymes, hypersensitivity to niacin, and arterial bleeding, as well as monitoring recommendations for blood pressure, glucose, uric acid, etc., due to niacins systemic effects)