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Results Baseline demographic and clinical characteristics In SURMOUNT-5, 425 participants had study-defined prediabetes at baseline (tirzepatide N = 215, semaglutide N = 210)

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Starting at the lowest dose of the new medication and escalating slowly provides the best opportunity to identify any recurring allodynia early

It is generally started at a low dose and gradually increased over time, every four weeks until a target dosage is reached