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The SUSTAIN-6 Trial (Once-Weekly Semaglutide) The Trial to Evaluate Cardiovascular and Other Long-term Outcomes with Semaglutide in Subjects with Type 2 Diabetes (SUSTAIN-6) consisted of 3297 people living with T2DM, 83% with established cardiovascular disease, receiving once-weekly semaglutide (0.5 and 1.0 mg) or placebo

These factors are known to affect the probability of reporting specific adverse events in spontaneous reporting systems and, therefore, may act as potential confounders in disproportionality analyses

This situation undermines the credibility of the reported outcomes and highlights the need for independent, peer-reviewed research

But because they have different receptor systems, pharmaceutical firms can place their products in different ways