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Glutamine, regulated by c-MYC, is facilitated by type 2 amino acid transport protein (ASCT2) and sodium-coupled neutral amino acid transport protein 5 (SN2) to cross the cell membrane, enter the cytoplasm, and be converted into glutamate by glutaminase (GLS/GLS2)

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This is because of their anti melanogenic effects, which prevent skin pigmentation and lead to skin lightening

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