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Dietary polyphenols can impact several proteins involved in many different aspects of our metabolism, including many pathways that are altered in HNC cancer cells

Certain medical conditions or medications could interact with prescription weight loss treatment, making it less effective or unsafe

Concomitant corticosteroids as a third immunosuppressive therapy when used to induce remission, may further increase the relative risk of serious and opportunistic infections

Given the growing body of literature on CHAC proteins, a comprehensive overview of all published work is beyond the scope of this review

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