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PubMed 18
The mechanism appears to involve both an anti-inflammatory effect on melanocytes and normalization of the barrier function
299 , H1568H1576 (2010)
Particularly in groups receiving 600 and 900 mg/kg, erythrocyte immunoadhesive function was notably compromised, as demonstrated by a significant decrease in erythrocyte C3b receptor rosette rate (E-C3bRR) and an increase in erythrocyte immune complex rosette rate (E-ICRR) (69)
First cardiovascular safety trial of a DPP-4 inhibitor in patients with T2DM and high cardiovascular risk, showing that saxagliptin does not augment MACE but increases hospitalization for heart failure
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