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HCT-116 cells transfected with LNA miR inhibitor showed a dramatic decline in miR-200c expression compared with the un-transfected and scrambled groups
308,309 These transient adaptive states may subsequently serve as reservoirs from which genetically resistant clones emerge
Belvisi MG, Stretton CD, Barnes PJ
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While numerous reviews have addressed individual aspects of the gutbrain axis in PD, the present work offers a distinct conceptual contribution by integrating immunemicrobiome interactions within a unified multisystem framework that explicitly links peripheral immune dysregulation to central neuroinflammatory cascades
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