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This enzymatic reaction consumes both nicotinamide and SAM, leading to depletion of NAD+ storesa critical coenzyme required for cellular energy production, DNA repair, and metabolic regulation
The supplementary NAD+ dose is 100200 mg IM, 2-3x per week
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On the 6th day the platform was removed and the researchers recorded the number of times the individual mice crossed the quadrant where the platform was previously located, over the course of 60 seconds [1]
Risk increases with poor injection hygiene, reuse of needles, or injection into non-sterile sites
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