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There were minimal microbiome differences between lean and obese controls, suggesting that diet composition and adiposity had limited effects
Some patients report a mild headache or a feeling of lightheadedness after an IM injection
Depending on your levels of deficiency or energy needs, B12 injections are commonly given weekly or monthly
Hydroxocobalamin is an excellent choice if you follow a vegan lifestyle
It is likely that the larger number of statistically significant changes to the microbiome observed in the groups switched from WD to LD reflects their more numerous exposures to different diets, longitudinal changes in dietary exposure, the stress associated with diet switch, the negative energy state achieved by treatment and/or diet-driven weight loss, or a combination of these factors, but it may also be related to differences in terminal body weight and fat mass since both adiposity and diet composition have been shown to modulate the mouse gut microbiome profile
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