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Satoh N, Ogawa Y, Katsuura G, Hayase M, Tsuji T, Imagawa K, et al
Here is a summary of what recent science tells us about the mental side of the GLP-1 journey
Mechanism of Action of Tirzepatide Tirzepatide mimics the action of natural human hormones to enhance insulin secretion, inhibit glucagon release, delay gastric emptying, and suppress appetite, thereby achieving blood glucose lowering and weight reduction effects
In June 2025, a large study of older adults with Type 2 diabetes found those who took a GLP-1 drug mostly semaglutide had a "substantially higher risk" of developing wet age-related macular degeneration, a rare type of the disease, than people with diabetes who didn't take the medication
To date, research findings have been mixed on whether GLP-1 receptor agonists can help break this cycle
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