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These findings suggest a direct neuroprotective action of dapagliflozin, independent of glycemic control, potentially contributing to the cardiovascular and renal benefits observed with SGLT2 inhibitors in clinical trials [20]
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However, its precise role in DOR and the therapeutic potential targeting pyroptosis pathways remain underexplored
Other neurotransmitters and hormones, such as [restricted term], cortisol, and leptin, also significantly influence fat metabolism and should not be overlooked
For example, the Wegovy label has been updated over time (including updates in 2025), reinforcing why patients should always confirm why they should use it with a licensed provider
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