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The second is dose and route translation : even where an effect is real in a mouse, the human-equivalent dose is not a simple body-weight scaling, and as the route section above stressed there is no human bioavailability figure to anchor an oral-versus-injected comparison
PMID: 27847966 Tertiary Organoprotection / Cytoprotection Broad-Spectrum Cytoprotective Signaling BPC-157 has been studied for its cytoprotective properties across multiple cell types, including gastric epithelial cells, hepatocytes, and endothelial cells
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this was not included in the tool since the definition of outliers is subjective
Thus, until this has been studied, parenteral vitamin B12 therapy is still to be recommended for such patients [26]
